Protease, Frozen

Novozym® 539

The key enzymatic activity of Novozym® 539 is provided by a serine endo-protease. It hydrolyzes internal peptide bonds. In diagnostics, that makes it highly suitable for lysis processes, as these need an efficient breakdown of viral cell walls. 

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Key Benefits Description Safe handling
  • A broad potential application range

    Novozym® 539 has the potential to be used in a broad range of viral diagnostic applications. These include influenza, HIV and COVID-19.

  • A recombinant product

    This is a recombinant product manufactured by microbial fermentation. 

Novozym® 539 is an intermediate nucleus-free product. It can be upgraded to your required product specifications.

Activity: 35 KNPU-S/g.

This product contains enzymes. While enzymes are safe to use in consumer applications, they need correct handling in working environments to ensure workers’ safety.

Indeed, repeated inhalation of enzyme dust or aerosols resulting from improper handling may induce sensitization and may cause allergic type 1 reactions in sensitized individuals.


Please follow the precautionary handling recommendations below:

  • Avoid breathing dust/fume/gas/mist/vapors/spray
  • Avoid contact with eyes, skin, or clothing
  • In case of inadequate ventilation wear respiratory protection
  • IF INHALED: Remove person to fresh air and keep comfortable for breathing
  • If experiencing respiratory symptoms: Call a POISON CENTER or a doctor
  • Store in a dry place. Store in a closed container
  • Dispose of contents/containers in accordance with local regulations


For more safety information, please watch the entire series of safety videos.