Lipases

Substitute your chemical catalysts with lipases from Novozymes

With impressive substrate selectivity and fast reaction rates, lipases are excellent catalysts offering both a sustainable and cost-efficient alternative in your manufacturing.

Fine Chemicals BioCatalysis lab workers

Future-proof your products with green chemistry

Conventional fine chemicals often suffer from a number of unsustainable traits, not least their petrochemical origin, scarce supply, and the fact that they can be pollutants that create waste.

At the same time companies need to demonstrate more sustainable manufacturing processes with a reduced environmental impact.

So how can you meet the growing demand for pharmaceuticals with cost-effective fine chemicals that leave no impact on our planet, its people, and animals?

The 12 Principles of green chemistry

Achieve more with lipases

Lipases are used in many industrial applications where the chemical transformations include enantioselective resolution of esters and amides.

Lipases catalyze the hydrolysis of triacylglycerol to different glycerol derivatives and free fatty acids. They also show diversified specificity for substrates and reactions under anhydrous conditions to synthesize new molecules by esterification, alcoholysis, transesterification and acylation.

Biocatalysis with lipases deliver cost savings, greater sustainability, and better productivity. You can also achieve higher-quality active pharmaceutical ingredients (APIs) and intermediates.

Fine chemicals achieve more icons

Our lipase solutions

Find the right solution for you in our global portfolio, shown below. To find out more about products available in your region, get in touch with your local Novozymes representative.

Enzymes from Novozymes are not compliant with pharmaceutical manufacturing standards. They should not be used as APIs or excipients.

Lipase application areas

Lipases are used in several industrial applications where the chemical transformations include enantioselective resolution of esters and amides, and other general transformations such as:

  • Acylation of alcohols and amines to form esters and amides
  • Mild hydrolysis or acylation of sensitive substrates
  • Kinetic resolution by transesterification of racemic acids and alcohols
  • Kinetic resolution by hydrolysis of racemic esters
  • Desymmetrization of diesters

Examples of commercial applications, where lipases are being deployed as catalysts are illustrated below.

Lipases round

Get expert advice on how to get started on your biocatalysis transition

We’re happy to put you in touch with our industry experts for advice on optimizing your process or finding the right solution or sample to meet your needs. Book a no-obligation meeting with our experts today and let them help you to:

  • Identify the right products or product class for your biocatalysis applications
  • Get technical support related to screening and selection of relevant enzyme samples to be tested in new experimental applications
  • Demonstrate the financial and environmental benefits of transitioning from chemicals to biocatalysis
expert photo

All our products for biocatalysis

Find the right solution for you in our global portfolio. To find out more about products available in your region, get in touch with your local Novozymes representative.

Our enzymes are not compliant with pharmaceutical manufacturing standards. They should not be used as APIs or excipients.

  Physical Form Grade pH Range Optimal temperature range, °C Safe handling
Sustine® 110 IM  Granulate (immobilized) Food grade 5-9 30-60°C Generic
Sustine® 111 Liquid Food grade 5-9 30-60°C Generic
Sustine® 121 Liquid Food grade 6-8 50-75°C Generic
Sustine® 140 Liquid Technical grade 7-10 30-70°C Generic

Novozymes is the world leader in biological solutions

With the world’s largest and most diverse collection of enzyme strains, coupled with a global, robust and reliable supply,  Novozymes is here to help you unlock the full potential of your biocatalysis route and make your manufacturing processes more sustainable.

Novozymes Lyngby Innovation Campus

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