Microbial protease, Granulate

NUE™ 6.0 T

NUE™ 6.0 T is a highly alkaline protease that delivers more efficient unhairing and consistently high pelt quality. With NUE™ 6.0 T, tanneries can reduce their use of auxiliary and standard liming agents, resulting in lower sulfide and COD loads. Used together with Greasex® Ultra, NUE™ 6.0 T  has a synergistic effect.

NUE™ 6.0 T is designed for further formulation.

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Key Benefits Description
  • Increases surface area and reduces wrinkles

    Lime-based swelling removes non-collagen, interfibrillar materials through osmotic forces. This leads to a reduction in surface area and the formation of wrinkles. The targeted action of this product induces swelling by breaking down non-collagen materials. That opens up collagen fibres, leading to an increase in surface area and reduction in wrinkles. 

  • Easier processing

    Various “cementing substances” surround the basement membrane of the hair root. These proteins include proteoglycans, glycosaminoglycans and dermatan sulfate. This product removes them. The result is excellent scud and hair loosening and an easier process.  

  • Improves softness, grain and dyeing properties

    By removing unwanted non-collagen materials this product improves softness. By improving scud and hair loosening it leaves a cleaner pelt, providing the basis for fine grain. A cleaner pelt and softer structure leads to greater uniformity which results in more even dyeing.  

  • Reduces sulfide loads in your wastewater

    Conventional unhairing processes use large amounts of sulfide. By breaking down the proteins that "cement" the hair, this product makes it easier to remove. That allows your customers to reduce their use of sulfide, which in turn reduces pollution levels.

  • Fully biodegradable

    This product is both biodegradable and renewable. That means it has minimal environmental impact.

NUE™ 6.0 T  breaks down the membranes that surround fat cells. That makes the fat accessible to Greasex® Ultra, which then breaks it down for improved dispersion.   NUE™ 6.0 T is suitable for both hair-saving and hair-burning processes. In hair saving, add  NUE™ 6.0 T before the lime addition. In hair burning, add it before the main sulfide addition. 

How alkaline proteases improve unhairing & liming in tanneries

Alkaline proteases break down the proteins in the substances that  "cement" the hair root. That loosens the hair which can then be degraded by chemical action. 


The main goal of unhairing and liming is to loosen and remove hair and epidermis. The process removes non-collagen substances​ and opens up the fiber structure. The structure's complexity can lead to process challenges. That can result in inadequate loosening of hair, enlarged bellies and/or loose grain and wrinkles. 

Unhairing & liming involves the use of lime and sodium sulfide. These are used in combination with liming auxiliaries such as sharpening agents and tensides. Modern processes also use readily biodegradable proteases. The complex raw material structure needs very specific alkaline proteases. These function as liming agents to speed up the reactions of the chemicals used. They also allow tanneries to reduce their chemical usage. 

“Cementing substances”  surround the basement membrane of the hair root. These substances include proteins like proteoglycans, glycosaminoglycans and dermatan sulfate.  Proteins consist of polypeptide chains of amino acids linked by peptide bonds. Proteases break down these bonds. In that way, proteases help remove the cementing proteins that surround the hair root. Proteases first loosen the hair, then chemical action degrades it.  

Combining alkaline proteases with alkaline lipases in unhairing & liming boosts the benefits. Lipases break down fats and oils. Proteases break down the membranes that surround fat cells. So proteases make the fat accessible to the lipase. This synergistic action improves fat dispersion.  Together, alkaline proteases and lipases deliver excellent hair and scud loosening. The result is​ a clean and relaxed pelt that is ready for the next step. Tanneries can add alkaline lipases and proteases at the early stage of unhairing. Alternatively, they can add them in hair burning, hair-saving, or at the end in the reliming process.  

NUE™ 6.0 T is a highly alkaline protease that delivers more efficient unhairing and consistently high pelt quality. With NUE™ 6.0 T, tanneries can reduce their use of auxiliary and standard liming agents, resulting in lower sulfide and COD loads. Used together with Greasex® Ultra, NUE™ 6.0 T  has a synergistic effect.

NUE™ 6.0 T is designed for further formulation.

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