Lipase, Immobilized (granular)

Lipozyme® TL IM

Get higher yields of better quality interesterified oils and fats with Lipozyme® TL IM. Enzymatic interesterification with Lipozyme® TL IM offers various advantages over chemical interesterification. It allows you to produce high-quality, trans fat-free oils and fats. These are suitable for trans fat-free margarine and other products. All without using harsh chemicals or generating unwanted by-products.  

Also available in 60 L pack size.

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Key Benefits Description Safe handling
  • Trans fat-free oils and fats

    This product is a selective biological catalyst. It does not generate trans fat in interesterification.

  • More cost-effective process

    This product interesterifies fat through a continuous process. This is a more cost-effective process than continuous running in chemical interesterification.

  • Simpler process

    The continuous process needed for this product takes fewer unit operations than chemical processes. It also cuts out the need for washing and post-bleaching.

  • Better safety

    With this product, you can completely avoid the use of hazardous chemical catalysts such as sodium methoxide. It works in a process with much lower temperatures than chemical ones.

  • Better quality oils and fats

    Unlike chemicals, it preserves natural anti-oxidants. That improves oxidative stability for better quality oils and fats.

  • Higher oil yields

    With this product you can avoid post-bleaching and associated oil losses in your process. That's because, unlike chemical processes, the enzymatic process doesn't generate unwanted by-products.

  • Lower capital cost

    The process needed for this product only needs simple reactors. That means putting this product in place takes lower capital investment than chemical interesterification.

  • More sustainability

    This product reduces energy use, acidification and smog formation. That can potentially result in greenhouse gas emission reductions. A life cycle assessment study showed CO2 reductions of up to 22% compared to chemical interesterification with this product.

Produce interesterified oils and fats more efficiently and sustainably with  Lipozyme® TL IM. The enzyme is immobilized on a carrier. This carrier rearranges the fatty acids preferentially, but not uniquely, in the Sn1- and Sn3-positions of the triglycerides. 

This product contains enzymes. While enzymes are safe to use in consumer applications, they need correct handling in working environments to ensure workers’ safety.

Indeed, repeated inhalation of enzyme dust or aerosols resulting from improper handling may induce sensitization and may cause allergic type 1 reactions in sensitized individuals.


Please follow the precautionary handling recommendations below:

  • Avoid breathing dust/fume/gas/mist/vapors/spray
  • Avoid contact with eyes, skin, or clothing
  • In case of inadequate ventilation wear respiratory protection
  • IF INHALED: Remove person to fresh air and keep comfortable for breathing
  • If experiencing respiratory symptoms: Call a POISON CENTER or a doctor
  • Store in a dry place. Store in a closed container
  • Dispose of contents/containers in accordance with local regulations


For more safety information, please watch the entire series of safety videos.